Essay: The Breakdown of Methionine in the Body

The breakdown of methionine in the body results in the production of Homocysteine. Methionine is converted by the action of the enzyme methionine adenosyltransferase (MAT) to S-adenosylmethionine (SAMe). This occurs in the normal pathway. The next phase after this is the hepatic phase II detoxification. In this phase, SAMe contributes a methyl group. It thus becomes S-adenosylhomocysteine (SAH).

This then becomes homocysteine after the loss of its adenosine. The recycling of homocysteine back to methionine must then occur. This takes place by accepting a methyl group from methylcobalmin. Methylcoblmin is recycled to methionine by the action of the addition of a methyl group to it. The methyl group is obtained from betaine. This is then converted into cysteine and taurine. This process takes place with the help of vitamins.

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